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Avance® Nerve Graft is allograft tissue for bridging nerve discontinuities. Avance® is a decellularized and cleansed extracellular matrix from donated human peripheral nerve. The cleaning process preserves the inherent and relevant structural characteristics of the tissue. This proprietary process removes cells and debris, axons and chondroitin sulfate proteoglycans (CSPG), natural axonal growth inhibitors. Avance® simply connects the proximal and distal ends of a transected nerve. Regenerating axons can grow through the allograft scaffold, into the patient’s distal nerve tissue toward the target muscle or skin. Similar to nerve autografts, Avance® provides the surgeon with desired handling and structural characteristics: pliability of soft tissue, an intact epineurium to suture the graft in place and intact endoneurial tubes for the axons to grow through. |








